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Instructions

1

Blood for the study of thyroid hormonessurrenders from the vein in the morning on an empty stomach. The analysis is carried out in the immunological laboratory of a medical and preventive institution. A laboratory study of the functional ability of the gland includes the determination of the following indices: T3 (triiodothyronine) total and free, T4 (thyroxine) total and free, TSH (thyroid-stimulating hormone of the pituitary), AT-TG (antibodies to thyroglobulin), AT-TPO (antibodies to thyroxine peroxidase). Triiodothyronine is a hormone secreted by the cells of the thyroid gland, responsible for controlling the oxidation-reduction processes in the body. Thyroxine is a producer of gland tissue that participates in the metabolism of proteins in the body. T4 is 10 times more active than T3. Antibodies to thyreperoxidase are autoantibodies to the enzyme released by thyroid gland cells that participate in the formation of triiodothyronine and thyroxine. Antibodies to thyroglobulin - antibodies, produced by thyroglobulin (a protein that is a precursor of hormones T3 and T4). A thyroid-stimulating hormone is a substance produced in the pituitary (in the brain) and controlling its work.

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With an increase in thyroid function T3 and T4begin to be produced in large quantities, which leads to the appearance of symptoms of hyperthyroidism: increased sweating, palpitations, weight loss. When the function is defective, the release of triiodothyronine and thyroxine decreases, which leads to the development of hypothyroidism with the following symptoms: slowing of the heartbeat, lowering of body temperature, lethargy. When immunity is violated, accompanied by the manifestation of his aggression against his body tissues, an increase in the production of antibodies to thyroid peroxidase occurs, which causes the development of autoimmune diseases. It is necessary to know that in each laboratory there are different values ​​of the norm depending on the method of analysis. When evaluating the results obtained, one should be guided by the norms indicated in the research form. The average normal indices in the test for hormones of the thyroid gland are: TTG - 0,4-4,0 mU / l, T3 - 2,6 - 5,7 pmol / l, T4 - 9,0 - 22,0 pmol / l , АТ-ТГ - 0 - 18 U / ml, АТ-TPO - <5,6 U / ml.

3

Based on the results of the study,Based on the knowledge of changes in hormone concentrations, one can assume the presence of the disease. With an elevated content of hormones T3 and T4, a decreased level of TSH against the background of normal indices of AT-TG and AT-TPO, it is possible to assume the presence of hyperthyroidism. Primary hypothyroidism (the source of the disease - the thyroid gland) is diagnosed on the basis of the following data: T3 and T4 - the norm or a small decrease, TSH - increase, AT-TG and AT-TPO - the norm. Reduced concentrations of T3, T4 and TTG, normal values ​​of AT-TG and AT-TPO indicate the development of secondary hypothyroidism (sources of the disease is the pituitary gland). To decipher the obtained results of the study, it is necessary to consult an endocrinologist who, if necessary, will prescribe an additional examination and laboratory tests.