How to combine paracetamol with other medicines
How to combine paracetamol with other medicines
Paracetamol is effectivean anti-inflammatory agent of the family of analgesics. Due to its peculiarities, Paracetamol is widely used for the treatment of various conditions, however, before using the drug, its interaction with other drugs should be studied in order to avoid undesirable drug medication.
Poisoning of the liver
Paracetamol has a negative effect onfunction of the liver, which causes its inadmissibility of use with various medicines. Thus, the use of an analgesic with antihistamines, as well as glucocorticoids, phenobarbital or ethacrynic acid is undesirable. An overdose on the background of using these medications can lead to toxic liver damage, which can be accompanied by severe consequences for other organs.Decreased effectiveness of drugs
Also, Paracetamol is incompatible withanticholinergics ("Atropin", "Hyoscyamine"). These drugs reduce the absorption of the drug and reduce its effectiveness, and therefore, it is necessary to refuse the use of this analgesic and consult with a doctor about the use of alternative methods of treatment. Oral contraceptives contribute to the rapid removal of "Paracetamol" from the system, which also may adversely affect therapeutic procedures. Also, the drug reduces the effectiveness of uricosuric drugs (drugs for gout - "Probenecid" or "Sulfinpirazon"). Thus, it is necessary to abandon the analgesic at the time of taking the drugs of this group. Paracetamol also worsens the effectiveness of Diazepam and Lamotrigine. It is dangerous to use the drug with Zidovudine because of the increased risk of increasing liver toxicity. Reduces the effects of Paracetamol drugs such as Isoniazid, Carbamazepine, Phenytoin, and Primidon. This is due to the fact that these drugs increase the metabolism of the drug and accelerate its removal from the body. Also, "Kolestyramin" reduces the effectiveness of anti-inflammatory therapy. "Metoclopramide", on the contrary, increases the concentration of paracetamol in the blood, which can also lead to undesirable consequences. Therefore, before combining Paracetamol with any of the above drugs, you should consult your doctor to prescribe an alternative analgesic medication or dosage adjustment. It should also be noted that Paracetamol is found in a large number of drugs against colds, flu and inflammation. Before using Paracetamol alone, examine the composition of your medication to treat other symptoms. Do not take Paracetamol along with one of the paracetamol-containing products, as this can lead to an overdose and the appearance of adverse reactions from the body.
